NIHR Funding Calls
i4i Programme
The invention for innovation (i4i) programme is a dedicated MedTech translational funding scheme for academics, clinicians and small- medium-sized enterprises(SME), which will advance innovative medical technologies and interventions for increased patient benefit in areas of existing or emerging clinical need. Projects must have already demonstrated proof of concept as a minimum. Applicants are expected to have generated experimental data to support the case for further development and illustrate technical feasibility, have sufficient research and activities planned (e.g. regulatory or health economics), and have a clear pathway towards adoption and commercialisation. Contact details for queries: i4i@nihr.ac.uk
The Efficacy and Mechanism Evaluation (EME) programme primarily funds clinical trials and other robustly designed studies that test the efficacy of interventions. It covers both new and repurposed interventions, including diagnostic tests and decision-making tools, therapeutics, psychological treatments, medical devices, and public health initiatives delivered by the NHS. EME also supports hypothesis-driven research within clinical trials into the mechanism of action of interventions. Applications are required to demonstrate some initial evidence that the technology may be efficacious in patients (i.e. a signal of efficacy in a relevant human population has already been achieved) but a large-scale study is needed to determine definitive proof of clinical efficacy. Contact details for queries: eme@nihr.ac.uk
The Health Technology Assessment (HTA) programme supports research that is immediately useful to patients, clinical practice, and policy or decision makers. It supports research into a wide range of technologies with the potential to improve health outcomes, including procedures, drugs, devices, diagnostic tests, settings of care and screening programmes. Studies funded by HTA aim to establish the clinical effectiveness or accuracy and cost-effectiveness of technologies in comparison with the current alternative(s) or within existing pathways. Applications to HTA are required to demonstrate that efficacy has already been established. Contact details for queries: htafunding@nihr.ac.uk
22/97 – Early detection of liver disease
The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this primary research topic. This funding call is looking for applications from researchers who can establish the most clinical and cost-effective method of selecting at risk people in primary care for referral to secondary care for management of chronic liver disease. Applications close at 13:00 on 25th January 2023. Click for further details and to access the application form.
22/98 – Low-dose computed tomography for the diagnosis of lung cancer in symptomatic patients seen in primary care
The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this primary research topic. This funding call is looking for applications from researchers who can assess the feasibility of conducting a study to examine the diagnostic performance of low-dose chest CT in the assessment of patients with symptoms that may suggest lung cancer. Applications close at 13:00 on 25th January 2023. Click for further details and to access the application form.
22/99 – Clinical prediction models for early-onset neonatal infection
The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this primary research topic. This funding call is looking for applications from researchers who can establish the accuracy of clinical prediction models for early-onset neonatal infection in the UK and establish their effectiveness in guiding management in the baby. Applications close at 13:00 on 25th January 2023. Click for further details and to access the application form.
22/101 – Management of bone metastasis and skeletal related events (SREs) in patients with advanced cancer
The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this primary research or evidence synthesis topic. The HTA Programme is interested in proposals for the evaluation of interventions related to the management of bone metastasis and skeletal related events (SREs) in patients with advanced cancer.
Applicants should clearly define and justify their choice of patient group, study design and outcome measures, and explain how the research will fit into the remit of the HTA Programme. Applications close at 13:00 on 4th January 2023. Click for further details and to access the application form.
22/114 – NIHR NICE rolling call (HTA Programme)
The Health Technology Assessment (HTA) Programme is accepting stage one applications to this funding opportunity. The programme is interested in receiving applications to meet recommendations in research identified in NICE guidance that has been published or updated since 2015. Applications close at 13:00 on 4th January 2023. Click for further details and to access the application form.
22/112 – Health Technology Assessment Programme researcher-led (primary research)
The Health Technology Assessment (HTA) Programme is accepting stage one applications to this funding opportunity. In this researcher-led workstream, grants are available for primary research and evidence synthesis on topics proposed by the researchers. Proposals should normally evaluate the clinical and cost effectiveness of a health technology. For diagnostic technologies, researchers may suggest equivalent evaluations. There is a particular call for applications relating to either winter pressures or brain tumours.
Applications close at 13:00 on 4th January 2023. Click for further details and to access the application form.
22/129 – Motor Neurone Disease highlight notice
The Health Technology Assessment (HTA) Programme is accepting stage one applications to this funding opportunity. This funding call invites proposals for Motor Neurone Disease research to address important health and social care questions. Applications close at 13:00 on 4th January 2023. Click for further details and to access the application form.
22/131 – Management of antipsychotic-induced sexual dysfunction
The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this primary research topic. They are looking to assess the clinical and cost-effectiveness of adjuvant medication (e.g. aripiprazole, phosphodiesterase-5 inhibitors) for the treatment of antipsychotic-induced sexual dysfunction. The study design will be a randomised controlled trial with adjuvant medication versus placebo and can be completed in any setting, as long as defined and justified by applicants.
Applications close at 13:00 on 29th March 2023. Click for further details and to access the application form.
22/166 Rehabilitation and care following stroke (HTA Programme)
The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this broad brief topic. The HTA Programme is interested in proposals for the evaluation of interventions, which already have some evidence to show that they can be effective, to improve the treatment, management and support given to adults following a stroke, which address, or partly address, one or more of the:
- Outputs from NHS England’s Demand Signalling in the area of Rehabilitation and life after stroke.
- Priorities from the James Lind Alliance Priority Setting Partnership in Stroke rehabilitation and long-term care.
Applications close at 13:00 on 29th March 2023. Click for further details and to access the application form.
Charity grants
Alzheimer’s Research UK
The Major project grant scheme provides funds for intermediate to large scale research projects.
Provided to cover salaries (research, technical, students etc), equipment, animal costs and running costs (consumables, travel etc). £50,000 to £350,000 for up to five years.
Closing Date: 25 January 2023
British Heart Foundation
Clinical Study Grants funded by the British Heart Foundation | BHF
For clinical trials and observational studies of specific patient groups, usually costing more than £350,000 or lasting more than 3 years. Preliminary application assessment panel meetings are currently planned to take place in:
- February 2023 – submit by 5pm Wednesday 18th January 2023
- May 2023 – submit by 5pm Wednesday 3rd May 2023
- September 2023 – submit by 5pm Wednesday 6th September 2023
- November 2023 – submit by 5pm Wednesday 25th October 2023
Cancer Research UK
Prevention and Population Research Project Award
Prevention and Population Research Awards provide support for focused research proposals centred on key questions in prevention and population research.
Up to £500,000, up to 3 years
Closing Date: 14 December 2022